کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3363964 1592120 2010 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The effect of Helicobacter pylori infection on growth velocity in young children from poor urban communities in Ecuador
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
The effect of Helicobacter pylori infection on growth velocity in young children from poor urban communities in Ecuador
چکیده انگلیسی

SummaryObjectiveTo characterize the potential effects of Helicobacter infections on growth velocity in low socioeconomic status young children in a developing country.MethodsChildren were recruited in poor suburbs of Quito, Ecuador. Normally nourished, mildly and substantially malnourished children (defined using weight-for-age Z-scores at recruitment) formed equal strata. Six height and weight measurements were collected during one year. Enrollment and exit serum samples were analyzed for anti-Helicobacter IgG and exit non-diarrheal feces tested for Helicobacter antigen.ResultsAmong 124 participants (enrollment age 19 ± 9 months), 76 (61%) excreted fecal antigen at exit (were infected). Of these, 44 were seropositive at least once (chronic infections) and 32 tested seronegative both times (new or acute phase infections). The adjusted linear growth velocity during follow-up in children with new infections was reduced by 9.7 (3.8, 15.6) mm/year compared to uninfected controls and 6.4 (0.0, 12.9) mm/year compared to children with chronic infections. The effects of Helicobacter infections on ponderal growth were not significant.ConclusionThese results suggest that linear growth velocity is reduced in young children during the initial phase of Helicobacter infection.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Infectious Diseases - Volume 14, Issue 9, September 2010, Pages e788–e791
نویسندگان
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