کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3365077 1592150 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Association of hemochromatosis with infectious diseases: expanding spectrum
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
Association of hemochromatosis with infectious diseases: expanding spectrum
چکیده انگلیسی

SummaryWithholding iron from potential pathogens is a host defense strategy. There is evidence that iron overload per se compromises the ability of phagocytes to kill microorganisms. Several hypotheses exist to explain the association of hemochromatosis with infection. A combination of mechanisms likely contributes to the increase in susceptibility to infection in these patients. A review of the current literature delineating various pathogens to which patients with hemochromatosis are potentially susceptible, and recent advances in the understanding of the association of hemochromatosis with infection, are discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Infectious Diseases - Volume 11, Issue 6, November 2007, Pages 482–487
نویسندگان
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