کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3365428 1218367 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Reduced incidence of Type 1 diabetes and Type 2 diabetes in systemic sclerosis: A nationwide cohort study
ترجمه فارسی عنوان
کاهش بروز دیابت نوع 1 و دیابت نوع 2 در مبتلایان به اسکلروز سیستمیک: یک مطالعه کوهورت در سراسر کشور
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ایمونولوژی، آلرژی و روماتولوژی
چکیده انگلیسی

ObjectivesThe purpose of this study is to investigate whether systemic sclerosis is a risk factor for diabetes.MethodsFrom Taiwan's National Health Insurance Research Database and Registry of Catastrophic Illness database, we enrolled patients with systemic sclerosis and controls. Each systemic sclerosis patient was matched to at most three controls by sex, age, month and year of first diagnosis. Standardized incidence ratio (SIR) of diabetes in systemic sclerosis patients, and 95% confidence interval (95% CI) were calculated. Cox hazard regression was used to calculate the hazard ratio (HR).ResultsA total of 2671 patients with systemic sclerosis and 7769 controls were enrolled. Patients with systemic sclerosis had decreased type 1 diabetes (SIR: 0.18, 95% CI = 0.04–0.82). In female groups, systemic sclerosis patients also had lower rates of incident type 1 diabetes (SIR: 0.21, 95% CI = 0.05–0.95). Male and female patients with systemic sclerosis both had lower rates of incident type 2 diabetes (SIR: 0.46, 95% CI = 0.29–0.72; SIR: 0.41, 95% CI = 0.33–0.51, respectively). Systemic sclerosis patients had decreased type 1 diabetes and type 2 diabetes (HR: 0.18, 95% CI = 0.04–0.74; HR: 0.42, 95% CI = 0.36–0.50, respectively) after adjusting for age and sex.ConclusionsThe results clearly showed that patients with systemic sclerosis had lower incidence of type 1 diabetes and type 2 diabetes compared to control subjects.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Joint Bone Spine - Volume 83, Issue 3, May 2016, Pages 307–313
نویسندگان
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