کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3378155 | 1220067 | 2012 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Complexity of β-lactamases among clinical Aeromonas isolates and its clinical implications Complexity of β-lactamases among clinical Aeromonas isolates and its clinical implications](/preview/png/3378155.png)
Aeromonas species, aquatic Gram-negative bacilli, distributed globally and ubiquitously in the natural environment, may be implicated in a variety of human diseases. They can produce various β-lactamases which confer resistance to a broad spectrum of β-lactams, and therefore in vitro susceptibility testing must be used to guide antimicrobial therapy. However, conventional in vitro susceptibility tests may sometimes fail to detect these β-lactamases, and hence raise a therapeutic challenge. In this review article, two chromosomally mediated β-lactamases (i.e., AmpC β-lactamases and metallo-β-lactamases) and acquired extended-spectrum β-lactamases in aeromonads are reviewed, and the clinical implications of the complexity of β-lactamases are discussed.
Journal: Journal of Microbiology, Immunology and Infection - Volume 45, Issue 6, December 2012, Pages 398–403