Neurological manifestations of dengue

Dengue, the most common arboviral disease is fast emerging as a global health problem. The incidence and geographical distribution of dengue have greatly increased in recent years. Neurological manifestations are considered a rare complication of dengue infection, although a wide range of them have been reported in literature. The exact incidence of various neurological complications is uncertain. The pathogenesis of neurological complications can be related to the systemic effects of the infection, neurotropic effect of the virus and immune mediated. Detection of IgM in CSF using ELISA has a high specificity. Mortality due to neurological involvement is low and patients die due to other multisystem involvement. In dengue-endemic areas, it is prudent and justified to include dengue in the differential diagnosis of patients with fever and acute neurological manifestations.