Prévalence de la résistance d'Escherichia coli isolés de prélèvements d'origine urinaire ou gastro-intestinale vis-à -vis de l'association amoxicilline-acide clavulanique et de divers antibiotiques

This study evaluates the prevalence of the resistance of E. coli against amoxicillin-clavulanic acid (AMC), and analyzed the results according to the susceptibility testing methods. Strains tested with the ATB Expression were more resistant than with the E-test or the reference agar dilution methods, resulting in an apparent high frequency of resistance for E. coli. The rate of E. coli resistant to AMC is low: 3.2% and 2% for strains isolated from urinary tract (UT) and gastrointestinal tract (GIT). Moreover, 67% of the strains with reduced susceptibility had MICs ≤ 8 mg/L. The percentage of resistance to nalidixic acid, norfloxacin and ciprofloxacin were 17.9%, 11.3% and 10.6% for the UT strains and 5%, 8.5% and 5.1% for the GIT strains, respectively. Considering the increase of fluoroquinolone resistance, AMC remains a useful antibiotic for the treatment of E. coli infections.