کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3400290 1593074 2012 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Sleep apnea in kidney transplant patients: Clinical correlates and comparison with pretransplant patients
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیماری های عفونی
پیش نمایش صفحه اول مقاله
Sleep apnea in kidney transplant patients: Clinical correlates and comparison with pretransplant patients
چکیده انگلیسی

BackgroundSleep disordered breathing (SDB) is a prevalent, but forgotten, cardiovascular (CV) risk factor in end-stage renal disease patients. Studies of SDB in renal transplant patients are few with mixed results.ObjectivesTo assess the prevalence and clinical correlates of SA in patients who received a kidney transplant, and to compare the prevalence of SA between waiting list and transplant patients.Subjects and methodsOur study included 40 clinically stable renal transplant patients and 15 patients awaiting transplantation. Patients with morbid obesity, diabetes, pulmonary disease or symptomatic heart failure were excluded from the study. All patients underwent overnight polysomnography, demographic and clinical data were also collected.ResultsWe found that the prevalence of SA was high in both the transplant and the waiting list groups (38% vs 47%). The severity of SA didn’t show significant difference in both groups (AHI = 9.6 vs 16.2). Moreover, we found a significant association between impaired renal function and the AHI in Tx patients. Also, SA was associated with difficult-to-treat hypertension in Tx patients as we found a significant association between the AHI and the systolic blood pressure as well as the number of prescribed antihypertensive drugs.ConclusionSA is as highly prevalent in Tx as in WL patients. Moreover, this high prevalence in the transplant patients could be a consequence of declining renal function. In addition, we propose that sleep apnea is a new risk factor for hypertension and cardiovascular events in kidney-transplanted patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Egyptian Journal of Chest Diseases and Tuberculosis - Volume 61, Issue 4, October 2012, Pages 453–458
نویسندگان
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