Laboratory confirmed health care-associated bloodstream infections: A Jordanian study

SummaryBackgroundFew studies have been conducted in Jordan related to health care associated bloodstream infections (HCABSIs). This study aims to examine epidemiology of HCABSIs among hospitalized adult patients in Jordan.MethodsA cohort study (N = 570; 445 confirmed HCABSIs, 125 uninfected patients) with a nested 1:1 matched case–control design (n = 125 in each group) was used based on data from one large referral hospital in Jordan over a period of 5 years. HCABSI cases were determined based on confirmed positive blood culture after 48 h of admission. The case–control analyses (n = 250 per group) matched on gender, age, same admission month and unit.ResultsThe overall incidence and mortality rates were 8.1 and 5.8 per 1000 admissions, respectively. Four-variable and three-variable multivariate models were proposed to explain the risk of HCABSIs in the matched analyses .The four-variable model consists of blood product (OR = 24.5), invasive procedures (OR = 4.3), renal failure (OR = 9.2), and presence of other infections (OR = 21.6). The three-variable model consists of recipient of blood product (OR = 19.7), invasive procedures (OR = 4.5), and renal failure (OR = 9.4).ConclusionsThis study is a pioneer study that examined risk factors, the associated HCABSIs in Jordan. Results from this study can be used to influence infection control plans in Jordan.

► Health care associated bloodstream infections are major health problem.
► Recipient of blood product, invasive procedures, and renal failure were predictors of HCABSIs
► Results from this study can be used to influence infection control plans in Jordan.