کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3446666 1595486 2012 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Immunogenicity of A 23-Valent Pneumococcal Polysaccharide Vaccine Among Mexican Children
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Immunogenicity of A 23-Valent Pneumococcal Polysaccharide Vaccine Among Mexican Children
چکیده انگلیسی

Background and AimsStreptococcus pneumoniae infection continues to be a major source of morbidity and mortality in children in Mexico. The aim of this study was to evaluate the immune response to six serotypes in children <5 years of age after immunization with a 23-valent pneumococcal polysaccharide vaccine.MethodsA prospective study was conducted among children aged from 18 months to 4 years. Pre- and postvaccination titers for the serotypes selected in this project demonstrate a substantial response among all age groups.ResultsWe identified mild adverse events in 62% of the participants in this study. No serious adverse events were reported during the study.ConclusionsPneumococcal polysaccharide vaccine produced adequate immunogenicity in all age groups evaluated.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Medical Research - Volume 43, Issue 5, July 2012, Pages 402–405
نویسندگان
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