کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3446908 1595516 2008 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Behavioral Effects of Omega-3 Fatty Acid Supplementation in Young Adults with Severe Autism: An Open Label Study
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Behavioral Effects of Omega-3 Fatty Acid Supplementation in Young Adults with Severe Autism: An Open Label Study
چکیده انگلیسی

BackgroundPilot findings seem to suggest a potential beneficial effect of omega-3 fatty acid (FA) supplementation on behavioral alterations in children with autism. However, data on the potential benefits of omega-3 supplements in young adults with severe autism are lacking. In the present study, we sought to explore this issue in an open label study.MethodsNineteen young adults with severe autism (CARS >40), aged 18–40 years, received two fish oil capsules per day [0.93 g of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) plus 5 mg of vitamin E to avoid lipid peroxidation] for 6 weeks. Subjects were assessed with an ad hoc caregiver questionnaire, the Rossago Behavioral Checklist, for the assessment of behavioral anomalies.ResultsNo significant improvements were observed with regard to the severity and frequency of problematic behaviors either during the active treatment period or during the post-treatment 6-week observation period. Moreover, no effect on the number of episodes and severity of behavior aberrations was observed.ConclusionsOur negative findings do not point toward a major effect of omega-3 FA supplementation on behavioral abnormalities in adults with severe autism. Further studies on larger sample sizes are warranted to shed more light on this important issue.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Medical Research - Volume 39, Issue 7, October 2008, Pages 682–685
نویسندگان
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