کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3484480 1233746 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Impact of estradiol monitoring on the prediction of intrauterine insemination outcome
ترجمه فارسی عنوان
تأثیر نظارت بر استرادیول بر پیش بینی نتیجه تلقیح داخل رحمی
کلمات کلیدی
تلقیح داخل رحمی، سطح ائسترایدیول، نتیجه میزان بارداری
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی

ObjectiveTo evaluate the predictive value of oestradiol levels on the day of human chorionic gonadotrophin (hCG) administration on intrauterine insemination success rate.MethodsThe present study included 206 intrauterine insemination (IUI) cycles performed between June 2011 and October 2012. All IUI cycles were preceded by ovarian stimulation with gonadotrophins starting on cycle day 3. A single IUI was performed 24–36 h after hCG administration. Binary logistic regression analysis was performed to define the covariates of IUI success. The main outcome measure, clinical pregnancy rate per cycle, was assessed according to the oestradiol level.ResultsWith LR+=2 and AUC = 0.73, ROC analysis revealed out the oestradiol level as 465 pg/mL to predict the pregnancy with 60% sensitivity and 66% specificity. Binary logistic regression analysis identified the presence of oestradiol levels higher than 465 pg/mL (p < 0.01, 95% CI = 0.147–0.687) and stimulation duration (p < 0.01, 95% CI = 0.201–0.705) as the covariates approached statistical significance for IUI success.ConclusionsOestradiol level >465 pg/mL on the day of hCG administration might point out advanced outcome on mild ovarian stimulation combined with insemination.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Taibah University Medical Sciences - Volume 9, Issue 1, March 2014, Pages 36–40
نویسندگان
, , , , ,