کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
35220 45081 2010 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Optimization of culture medium for cordycepin production using Cordyceps militaris mutant obtained by ion beam irradiation
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Optimization of culture medium for cordycepin production using Cordyceps militaris mutant obtained by ion beam irradiation
چکیده انگلیسی

The effect of medium components on cordycepin production by Cordyceps militaris mutant obtained by ion beam irradiation was investigated. According to the response surface analysis using a central composite design for the prospective mutant G81-3, the predicted optimal concentrations of glucose as the carbon source and the yeast extract as the nitrogen source were 86.2 g/l and 93.8 g/l, respectively, and 6.84 g/l cordycepin was obtained. To date, this is the highest value for cordycepin production. The optimal concentrations of glucose and yeast extract for cordycepin production of the mutant was much higher than that of control (wild strain) and the cordycepin production was 2.79 times higher. Therefore, this new mutant will be a promising strain for future higher cordycepin production at industrial levels.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Process Biochemistry - Volume 45, Issue 1, January 2010, Pages 129–132
نویسندگان
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