کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
371373 621916 2009 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nitric oxide and interlukin-6 levels in intellectual disability adults with epilepsy
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Nitric oxide and interlukin-6 levels in intellectual disability adults with epilepsy
چکیده انگلیسی

Nitric oxide (NO) and interlukin-6 (IL-6) are highly reactive mediators that have been shown to play different roles in a variety of different biological process. The role of NO and IL-6 in the neuropathogenesis of brain seizures is still questionable. In order to evaluate the role of NO and IL-6 in neurological disorders such as seizures, we investigated 19 adults with intellectual disability (ID) who suffer from epilepsy and treated for convulsions. NO metabolites (NOx) and IL-6 levels in serum obtained after night-sleep were significantly high among ID individuals diagnosed with epilepsy versus ID people without epilepsy. These results indicated that NOx and IL-6 may have a pathophysiological role in convulsions. Consequently, we suggest that professionals consider chemical inhibitors that might be helpful against the function of NO and IL-6.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Developmental Disabilities - Volume 30, Issue 3, May–June 2009, Pages 567–571
نویسندگان
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