کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3897 197 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Peroxidase-mediated oxidation of l-dopa: A kinetic approach
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Peroxidase-mediated oxidation of l-dopa: A kinetic approach
چکیده انگلیسی

A kinetic model able to adequately describe the accumulation of p-topaquinone in peroxidase-mediated oxidation of l-dopa was developed, and the rate constants for both enzymatic and non-enzymatic branch were estimated either experimentally or using a computing program for detailed kinetic simulation. It is demonstrated that the accumulation of p-topaquinone in significant amounts occurred in excess of hydrogen peroxide or during auto-oxidation of l-dopa, but changes in the ratio of initial concentrations of the reactants can reduce considerably the production of this intermediate.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochemical Engineering Journal - Volume 52, Issues 2–3, 15 November 2010, Pages 248–254
نویسندگان
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