کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3915175 1251498 2009 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Bone mineral density in young women aged 19–24 after 4–5 years of exclusive and mixed use of hormonal contraception
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
Bone mineral density in young women aged 19–24 after 4–5 years of exclusive and mixed use of hormonal contraception
چکیده انگلیسی

BackgroundUse of depot-medroxyprogesterone acetate (DMPA), norethisterone enanthate (NET-EN) and low-dose combined oral contraceptives (COCs) has been associated with loss of bone mineral density (BMD) in adolescents. However, the effect of using a combination of these methods over time in this age group is limited. The aim of this cross-sectional study was to investigate BMD in young women (aged 19–24 years) with a history of mixed hormonal contraceptive use.Study DesignBMD was measured at the spine, hip and femoral neck using dual X-ray absorptiometry. Women were classified into three groups: (1) injectable users (DMPA, NET-EN or both) (n=40), (2) mixed COC and injectable users (n=13) and (3) non-user control (n=41).ResultsWomen in the injectables-only user group were found to have lower BMDs compared to the non-user group at all three sites, and there was evidence of a difference in BMD between these two groups at the spine after adjusting for body mass index (p=.042), hip (p=.025) and femoral neck (p=.023). The mixed COC/injectable user group BMD values were lower than those for controls; however, there was no evidence of a significant difference between this group and the non-user group at any of the three sites.ConclusionThis study suggests that BMD is lower in long-term injectable users but not when women have mixed injectable and COC use.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Contraception - Volume 80, Issue 2, August 2009, Pages 128–132
نویسندگان
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