Endometrial cancer: A review and current management strategies: Part I

• We present risk factors for endometrial cancer, including genetic predisposition.
• We review the diagnostic and metastatic evaluation of women with endometrial cancer.
• We describe the surgical management of early and advanced endometrial cancer.

Endometrial carcinoma is the most common gynecologic malignancy. A thorough understanding of the epidemiology, pathophysiology, and management strategies for this cancer allows the obstetrician–gynecologist to identify women at increased risk, contribute toward risk reduction, and facilitate early diagnosis. The Society of Gynecologic Oncology's Clinical Practice Committee has reviewed the literature and created evidence-based practice recommendations for diagnosis and treatment. This article examines:
• Risk factors, including genetic predisposition
• Diagnostic and metastatic evaluation
• Surgical management of early and advanced cancer, including lymphadenectomy in early cancer.