The effect of bed rest after intrauterine insemination on pregnancy outcome

ObjectiveTo compare the effect of bed rest after intrauterine insemination for 5, 10 and 20 mins on the pregnancy rate.DesignRandomized controlled trial.SettingIntegrated Fertility Center and Agial Fertility Center.SampleThree hundred and 96 couples with mild male factor, cervical factor, or unexplained infertility between the periods from 1/2012 to 12/2012.MethodsIntrauterine insemination with controlled ovarian hyper-stimulation.Main outcome measuresThe chemical and clinical pregnancy rates.ResultsThe couples were randomly subdivided equally into three groups: A, B, & C and they allocated for bed rest for 5, 10 and 20 min, respectively after insemination, the chemical and clinical pregnancy rates in group A (6.1% and 4.5%, respectively) were significantly lower than in group B (18.2% and 15.9%, respectively), and also they were significantly lower than in group C (23.5% and 19.7%, respectively), but there was no statistically significant difference in the pregnancy rates between groups B and C.ConclusionsBed rest for 10 and 20 min after intrauterine insemination has a positive effect on the pregnancy rate, but there is no statistically significance difference between them. We recommend bed rest for at least 10 min after intrauterine insemination.