Pregnancy rates following three different timings of intrauterine insemination for women with unexplained infertility: A randomised controlled trial

ObjectiveTo compare pregnancy rates following three different timings of intrauterine insemination after human chorionic gonadotrophin administration at 24, 34 and 48h in women with unexplained infertility.SettingKasr El-Aini Hospital.DesignRandomized controlled trial.Participants and methodsCouples with unexplained infertility had 125 cycles of IUI divided in three groups: Group (1): 24h after hCG administration, Group (2): 34h after hCG administration and Group (3): 48h after hCG administration.ResultsThere was no significant difference in pregnancy rates between all groups, Group 1 vs. Group 2 OR=0.61, 95% [CI] 0.15–2.36, Group 1 vs. Group 3 OR=0.42, 95% CI 0.12–1.53 and Group 2 vs. Group 3 OR=0.729, CI 0.23–2.32.ConclusionIUI can be done any time between 24 and 48h after hCG injection without significant differences in pregnancy rates.