Alcohol amination with heterogeneous ruthenium hydroxyapatite catalysts

• Intermolecular alcohol amination is accomplished with ruthenium on hydroxyapatite.
• No base additives or pretreatments are required.
• The catalyst is heterogeneous, as proven by hot filtration.
• Both aromatic and aliphatic amines are alkylated with benzyl alcohol or 1-octanol.

The intermolecular amination of alcohols was performed with ruthenium (Ru3+) immobilized on a calcium hydroxyapatite support. No additional base additives were necessary, nor did the catalyst require base treatment prior to reaction. High conversions were obtained with different amine and alcohol reactants.

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