کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4032992 1603043 2009 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Gene Therapy Targeting Glaucoma: Where Are We?
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی چشم پزشکی
پیش نمایش صفحه اول مقاله
Gene Therapy Targeting Glaucoma: Where Are We?
چکیده انگلیسی

In a chronic disease such as glaucoma, a therapy that provides a long lasting local effect with minimal systemic side effects, while circumventing the issue of patient compliance, is very attractive. The field of gene therapy is growing rapidly and ocular applications are expanding. Our understanding of the molecular pathogenesis of glaucoma is leading to greater specificity in ocular tissue targeting. Improvements in gene delivery techniques, refinement of vector construction methods, and development of better animal models combine to bring this potential therapy closer to reality.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Survey of Ophthalmology - Volume 54, Issue 4, July–August 2009, Pages 472–486
نویسندگان
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