کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4064436 1604187 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Motor unit number estimation as a complementary test to routine electromyography in the diagnosis of amyotrophic lateral sclerosis
ترجمه فارسی عنوان
برآورد تعداد واحد موتور به عنوان یک آزمون مکمل برای الکترومیوگرافی معمول در تشخیص اسکلروز جانبی آمیوتروفی
کلمات کلیدی
برآورد تعداد واحد موتور، الکترومیوگرافی، اسکلروز جانبی جانبی آمیوتروفیک
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی ارتوپدی، پزشکی ورزشی و توانبخشی
چکیده انگلیسی

Electromyographic (EMG) abnormalities that reveal denervation and reinnervation caused by lower motor neuron degeneration do not reflect the number of motor units that determines muscle strength. Consequently, motor unit activity potential (MUAP) parameters do not reflect muscle dysfunction.The aim of the study was to compare the value of motor unit number estimation (MUNE) and MUAP parameters as indicators of clinical muscle dysfunction in patients with amyotrophic lateral sclerosis (ALS), and to analyze the role of MUNE as a supplement to the EMG criteria for the diagnosis of ALS.In 25 patients with ALS, MUNE by the multipoint incremental method in the abductor digiti minimi (ADM) and quantitative EMG in the first dorsal interosseous (FDI) were obtained. The Medical Research Council (MRC) scale was used to evaluate clinical muscle dysfunction. A strong correlation between the number of motor units evaluated by MUNE and ADM clinical function by the MRC scale was found (P < 0.001). An increased value of surface-detected single motor action potential was associated with a decreased MRC score for ADM (P < 0.1). No relation was found between MUAP parameters in FDI and MRC scores. Our data support the value of the MUNE method for the detection of motor unit loss in ALS, and it could be postulated that MUNE studies may be considered complementary tests for ALS in a future revision of ALS criteria.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Electromyography and Kinesiology - Volume 26, February 2016, Pages 60–65
نویسندگان
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