Injection Therapy in the Management of Musculoskeletal Injuries of the Knee

Injections of the knee joint and the surrounding structures are one of the most common interventions performed by providers of musculoskeletal care. With appropriate patient selection, injections may provide substantial short-term relief with infrequent complications. Longer-term outcomes, including modification of the underlying disease processes, are debated within the literature. In this review, we provide an overview of injection therapy in and around the knee, with a focus on the indications, complications, pertinent techniques (including preparation, approaches, and aftercare), types of injectables (corticosteroids, viscosupplementation, and platelet-rich plasma), and evidence-based recommendations for roles of injection therapy in both intra- and extra-articular disease processes.