کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4116909 1270286 2006 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Genetic Deafness in Chinese Population
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب سلولی و مولکولی
پیش نمایش صفحه اول مقاله
The Genetic Deafness in Chinese Population
چکیده انگلیسی

Deafness is an etiologically heterogeneous trait with many known genetic, environmental causes or a combination thereof. The identification of more than 120 independent genes for deafness has provided profound new insights into the pathophysiology of hearing. However, recent findings indicate that a large proportion of both syndromic and nonsyndromic forms of deafness in Chinese population are caused by a small number of mutations. This review is focused on syndromic and nonsyndromic deafness as well as on the latest information linking inherited mitochondrial pathologies to a variety of etiologies of sensorineural deafness in Chinese population. Better understanding of the genetic causes of deafness in Chinese population is important for accurate genetics counseling and early diagnosis for timely intervention and treatment options.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Otology - Volume 1, Issue 1, June 2006, Pages 1–10
نویسندگان
, , ,