Cartilaginous neoplasms of soft tissue and joints

Cartilaginous neoplasms of soft tissue and synovium are relatively uncommon. The vast majority is benign and the neoplastic matrix is usually hyaline in type. The heterogeneity in their histologic features, especially the degree of cellularity and cytological atypia may pose challenges in diagnosis. Immunohistochemistry and molecular analyses are helpful in only specific circumstances stressing the importance of accurate histologic interpretation.