کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4131520 1271240 2011 16 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Molecular pathology of thyroid cancer
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی آسیب‌شناسی و فناوری پزشکی
پیش نمایش صفحه اول مقاله
Molecular pathology of thyroid cancer
چکیده انگلیسی

Thyroid cancer is increasing in incidence. Although often indolent and highly curable neoplasms, they may recur, metastasize, or become resistant to radio-iodine therapy. Advances in understanding the molecular mechanisms that lead to the development and progression of these neoplasms provide opportunity for prevention, effective early identification and targeted therapies for management of aggressive cancers. We review the molecular alterations implicated in thyroid cancer initiation and progression, gene expression profiling and microRNA studies, as well as the results of emerging new data from genome-wide association and single-nucleotide polymorphism (SNP) analyses.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diagnostic Histopathology - Volume 17, Issue 3, March 2011, Pages 124–139
نویسندگان
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