Lymph node pathology in the HIV-positive child

Lymphadenopathy in the HIV-positive child may be due to a range of non-neoplastic (non-infective and infective) and neoplastic conditions. Reactive changes and infective diseases, mostly of mycobacterial aetiology, are encountered most often. The common neoplastic conditions include non-Hodgkin lymphoma (Burkitt lymphoma and diffuse large B- cell lymphoma) and Kaposi sarcoma.