Condrosarcoma. Variantes de condrosarcoma

The term chondrosarcoma is used for describing a heterogeneous group of tumors with diverse morphological features and clinical behaviour. It is assumed that chondrosarcomas are malignant tumors composed of cells with a cartilaginous phenotype that usually show a lobulated histological pattern and tend to maintain their essentially cartilaginous nature along their evolution, independently of the site of the tumor, as well in osseous as in extra skeletal tumors. Several variants of chondrosarcomas are recognized. They have different morphological, radiological and clinical features. In this revision the above mentioned features of the different variants and the diagnostic difficulties for the pathologist are commented, and emphasis is given to the criteria for its differential diagnosis, including recent knowledge about cytogenetics and molecular biology.