کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4140607 | 1272261 | 2007 | 7 صفحه PDF | دانلود رایگان |

ObjectiveTo determine rates and types of adverse drug events (ADEs) in the pediatric ambulatory setting.MethodsA prospective cohort study at 6 office practices in the greater Boston area was conducted over 2-month periods. Duplicate prescription review, telephone surveys 10 days and 2 months after visit, and chart reviews were done. A 2-physician panel classified the severity, preventability, and ability to ameliorate (ie, if the severity or duration of the side effect could have been mitigated by improved communication) ADEs.ResultsWe identified 57 preventable ADEs (rate 3%; 95% confidence intervals [CI], 3%–4%) and 226 nonpreventable ADEs (rate 13%; 95% CI, 11%–15%) in the medical care of 1788 patients. Of the ADEs, 152 (54%) were able to be ameliorated. None of the preventable ADEs were life threatening, although 8 (14%) were serious. Forty (70%) of the preventable ADEs were related to parent drug administration. Improved communication between health care providers and parents and improved communication between pharmacists and parents, whether in the office or in the pharmacy, were judged to be the prevention strategies with greatest potential.ConclusionsPatient harm from medication use was common in the pediatric ambulatory setting. Errors in home medication administration resulted in the majority of preventable ADEs. Approximately one fifth of ADEs were potentially preventable and many more were potentially able to be ameliorated. Rates of ADEs due to errors are comparable in children and adults despite less medication utilization in children.
Journal: Ambulatory Pediatrics - Volume 7, Issue 5, September 2007, Pages 383–389