Use of an omega-3 fatty acid–based emulsion in the treatment of parenteral nutrition–induced cholestasis in patients with microvillous inclusion disease

Microvillous inclusion disease is a congenital intestinal epithelial cell disorder leading to lifelong intestinal failure. In this report, we discuss the use of a fish oil–based lipid emulsion in the treatment of 3 patients with microvillous inclusion disease who developed parenteral nutrition–associated liver disease.