Economic analysis of continuous antibiotic prophylaxis for prevention of urinary tract infections in infants with high-grade hydronephrosis

To prevent UTIs within the first 2 years of life in infants with high-grade hydronephrosis, this probabilistic model has shown that CAP use is a prudent expenditure of healthcare resources when compared to no CAP.Table. Base case results.Treatment armExpected valueCost (CAD$)Number of UTIsNumber of inpatient UTIsQuality-adjusted life yearsContinuous antibiotic prophylaxis1571.190.2040.0101.6986No continuous antibiotic prophylaxis1956.440.4180.0491.6985Incremental (continuous antibiotic prophylaxis - no continuous antibiotic prophylaxis)−385.25−0.213−0.0390.0001