Can urinary nerve growth factor and bladder wall thickness correlation in children have a potential role to predict the outcome of non-monosymptomatic nocturnal enuresis?

BWTh measurements and NGF/Cr values, as non-invasive tools, may guide therapy and improve outcomes in the treatment of children with NMNE. Further studies including a larger number of patients would be of great interest.131Figure. Sensitivity and specificity of BWTh and NGF/Cr in predicting LUTS of NMNE (BWTh sensitivity 95%, specificity 85.7%, cut-off 3.00, AUC 937; 95%; NGF/Cr sensitivity 97.5%, specificity 98.6%, cut-off 0.885, AUC 999; 95%).