کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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4162887 | 1274293 | 2012 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Ileal bladder augmentation and vitamin B12: Levels decrease with time after surgery Ileal bladder augmentation and vitamin B12: Levels decrease with time after surgery](/preview/png/4162887.png)
ObjectiveWe investigated vitamin B12 deficiency following ileocystoplasty in children.MethodsPatients who underwent ileocystoplasty between December 1993 and September 2006 were included and B12 levels were retrospectively analysed. Patients with a serum B12 of less than 150 pg/ml were considered deficient. The distance of the ileal segment from the ileocaecal valve was recorded.ResultsThere were 105 patients in the series; 61 were male. Mean age at surgery was 7.7 years (SD = 3.9). The mean interval from surgery to most recent B12 level was 50 months (SD = 30). None of the patients were on B12 supplementation. Two patients were B12 deficient, both more than 7 years after surgery; 44% of patients with levels available 7 years after surgery had a B12 below 300 pg/ml. There was a significant negative correlation between B12 level and length of follow up (Spearman’s rank, P < 0.01). Twenty patients with an ileal segment sparing 60 cm from the ileocaecal valve had a higher mean B12 (524 vs 419, SEM 60 vs 28). This was not statistically significant.ConclusionWe demonstrate a reduction in serum B12 level with time following ileocystoplasty. These patients should have their B12 levels measured in the long term.
Journal: Journal of Pediatric Urology - Volume 8, Issue 1, February 2012, Pages 47–50