کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4172713 1275770 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Preventing necrotizing enterocolitis in very low birth weight infants: current evidence
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
Preventing necrotizing enterocolitis in very low birth weight infants: current evidence
چکیده انگلیسی

Necrotizing enterocolitis (NEC) is the most common serious gastrointestinal disorder affecting very preterm or very low birth weight infants. The risk is inversely proportional to gestational age and weight at birth. Fetal growth restriction and compromise may be additional specific risk factors. Postnatally, a variety of practices have been implicated in the pathogenesis of NEC including formula milk feeding, early and rapid advancement of enteral feed volumes, and exposure to H2-receptor antagonists. NEC, particularly severe NEC requiring surgical intervention, is associated with acute morbidity and mortality, prolonged hospital stay, and adverse long-term neuro-developmental outcomes. With the exception of feeding with human milk, only limited evidence is currently available to support interventions to prevent NEC. Promising strategies that merit further evaluation in randomized controlled trials include the use of standardized feeding protocols and immuno-prophylaxis with prebiotics and probiotics.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Paediatrics and Child Health - Volume 21, Issue 6, June 2011, Pages 258–264
نویسندگان
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