کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4205025 | 1279658 | 2007 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Agonistas adrenérgicos β2 y corticoides
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
پزشکی ریوی و تنفسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Agonistas adrenérgicos β2 y corticoides Agonistas adrenérgicos β2 y corticoides](/preview/png/4205025.png)
چکیده انگلیسی
Chronic obstructive pulmonary disease (COPD) is characterized by the presence of only partially reversible airflow obstruction that develops as a result of an anomalous inflammatory reaction to harmful substances, usually tobacco smoke. Drug treatment is therefore based on the use of bronchodilators and antiinflammatory agents, i.e. inhaled corticosteroids. Among bronchodilators, beta-2 agonists act by relaxing smooth muscle fibers, but an additional antiinflammatory mechanism has also been described. Although these drugs do not halt disease progression, they improve lung function and reduce symptoms. These improvements are more evident with the use of long-acting beta-2 agonists, which are also associated with a reduction in exacerbations and an increase in exercise tolerance. Therefore, short-acting beta-2 agonists are currently recommended in patients with mild disease and few symptoms while long-acting beta-2 adrenergic agonists are recommended patients requiring regular treatment. Inhaled corticosteroids are most effective in patients with severe COPD, in whom these drugs are recommended as they improve quality of life and reduce the number of exacerbations. There is also increasing evidence that inhaled corticosteroids can reduce mortality, which could change current recommendations.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archivos de BronconeumologÃa - Volume 43, Supplement 4, 2007, Pages 11-17
Journal: Archivos de BronconeumologÃa - Volume 43, Supplement 4, 2007, Pages 11-17
نویسندگان
Pilar de Lucas Ramos, Alicia Ferreiro, José Miguel RodrÃguez González-Moro,