کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4211792 1280651 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Clinical characteristics of health care-associated pneumonia in a Korean teaching hospital
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی ریوی و تنفسی
پیش نمایش صفحه اول مقاله
Clinical characteristics of health care-associated pneumonia in a Korean teaching hospital
چکیده انگلیسی

SummaryBackgroundHealth care-associated pneumonia (HCAP) has been proposed as a new category of respiratory infection. ATS/IDSA guidelines state that all patients with HCAP should receive empirical therapy directed at multidrug-resistant pathogens. However, recent data from other countries have reported a different picture of HCAP.MethodsWe conducted a retrospective observational study of patients with HCAP and CAP who were hospitalized through the emergency department in January–December 2008 at Samsung Medical Center, Seoul, Korea, and compared clinical characteristics, severity, distribution of pathogen, and outcomes.ResultsIn total, 345 patients hospitalized with pneumonia were eligible, 182 (52.8%) with HCAP and 163 (47.2%) with CAP. Patients with HCAP had greater comorbidity and higher Pneumonia Severity Index (PSI) score (P < 0.001). Although Streptococcus pneumoniae was the most frequently isolated pathogen in HCAP and CAP patients, the occurrence of potentially drug-resistant pathogens (29.3% vs. 13.0%; P = 0.044) and inappropriate initial antimicrobial treatment (24.6% vs. 8.7%; P = 0.032) were significantly higher in HCAP patients. Patients with HCAP had a longer duration of hospital stay (13 [8–18] vs. 8 [6–12] days; P < 0.001), and higher in-hospital mortality (19.2% vs. 7.4%; P = 0.001). In a multiple logistic regression analysis, however, in-hospital mortality was independently associated with higher PSI class (OR 2.82, 95% CI 1.19–6.70) and ICU admission (OR 15.37, 95% CI 3.58–66.05).ConclusionsSeverity of illness, rather than type of pneumonia, was the main predicting factor for in-hospital mortality among patients with pneumonia hospitalized through the emergency department.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Respiratory Medicine - Volume 104, Issue 11, November 2010, Pages 1729–1735
نویسندگان
, , , , , , , , ,