Dyslipidemia as a long-term marker for survival in pulmonary embolism

ObjectivesTo analyse survival rate after 24 months in consecutive patients with a diagnosis of PE as well as associated factors.MethodsProspective cohort study during a follow-up period of two years in a series of consecutive patients with PE.ResultsDuring the follow-up period, 34 out of 148 patients died (23%). Factors independently associated with reduced survival rate were: creatinine levels > 2 (OR, 8.8; 95% CI, 1.1 - 70.87), previous neoplasm (OR, 8.8; 95% CI, 3.69 - 20.98), dementia (OR, 6.85; 95% CI, 2.1 - 22.33) and dyslipidemia (OR, 5.07; 95% CI, 1.92 - 13.44). Forty four percent of the patients with dyslipidemia died vs. 20.8% of patients without this condition.ConclusionsIn our study dyslipidemia shows as a long-term negative prognostic marker for survival in patients with EP.

ResumoObjetivosAnalisar a taxa de sobrevivência após 24 meses, em pacientes consecutivos com diagnóstico de PE, bem como fatores associados.MétodosEstudo prospectivo durante um período de seguimento de dois anos em uma série consecutiva de pacientes com PE.ResultadosDurante o período de acompanhamento, 34 dos 148 pacientes morreram (23%). Fatores independentemente associados à reduzida taxa de sobrevivência foram: os níveis de creatinina> 2 (OR, 8,8; 95% CI, 1,1-70,87), neoplasia anterior (OR, 8,8; IC 95%, 3,69-20,98), demência (OR, 6,85; 95% CI, 2,1-22,33) e dislipidemia (OR, 5,07; IC 95%, 1,92-13,44). Quarenta e quatro por cento dos pacientes com dislipidemia morreram contra 20,8% dos pacientes sem essa condição.ConclusõesNo nosso estudo, a dislipidemia mostra-se um marcador prognóstico negativo de longo prazo na sobrevida de pacientes com EP.