کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4251 217 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Compactin production in solid-state fermentation using orthogonal array method by P. brevicompactum
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Compactin production in solid-state fermentation using orthogonal array method by P. brevicompactum
چکیده انگلیسی

In the present study, compactin production by Penicillium brevicompactum WA 2315 was studied using solid-state fermentation. Initially, various agro-industrial residues were screened as a support and carbon source. The effect of various process parameters such as initial moisture content, incubation time, effect of additional carbon and nitrogen supplementation were studied by single factor optimization for improved compactin production. Subsequently, levels of supplement components were studied statistically using Taguchi orthogonal array (L25-orthogonal array). Out of six parameters studied using L25 array, glycerol was the most significant contributor to compactin production. The supplements at optimized levels resulted in a compactin production of 771 μg/gds (microgram/gram of dry substrate). Subsequent studies resulted in further improvement of compactin yield by varying the pH of the supplement solution and an initial pH 7.5 resulted in a compactin yield of 815 μg/gds.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biochemical Engineering Journal - Volume 41, Issue 3, 1 October 2008, Pages 295–300
نویسندگان
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