کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4267929 1610731 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Silodosin vs tamsulosin in the management of distal ureteric stones: A prospective randomised study
ترجمه فارسی عنوان
سیلوودزین در مقابل تامسولوزین در مدیریت سنگ های دمانس اوره: یک مطالعه تصادفی آیندهنگر
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی اورولوژی
چکیده انگلیسی

ObjectivesTo compare the efficacy of silodosin (8 mg) vs tamsulosin (0.4 mg), as a medical expulsive therapy, in the management of distal ureteric stones (DUS) in terms of stone clearance rate and stone expulsion time.Patients and methodsA prospective randomised study was conducted on 115 patients, aged 21–55 years, who had unilateral DUS of ⩽10 mm. Patients were divided into two groups. Group 1 received silodosin (8 mg) and Group 2 received tamsulosin (0.4 mg) daily for 1 month. The patients were followed-up by ultrasonography, plain abdominal radiograph of the kidneys, ureters and bladder, and computed tomography (in some cases).ResultsThere was a significantly higher stone clearance rate of 83% in Group 1 vs 57% in Group 2 (P = 0.007). Group 1 also showed a significant advantage for stone expulsion time and analgesic use. Four patients, two in each group, discontinued the treatment in first few days due to side-effects (orthostatic hypotension). No severe complications were recorded during the treatment period. Retrograde ejaculation was recorded in nine and three patients in Groups 1 and 2, respectively.ConclusionOur data show that silodosin is more effective than tamsulosin in the management of DUS for stone clearance rates and stone expulsion times. A multicentre study on larger scale is needed to confirm the efficacy and safety of silodosin.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Arab Journal of Urology - Volume 14, Issue 1, March 2016, Pages 12–17
نویسندگان
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