Sonic Hedgehog Regulates Brain‐Derived Neurotrophic Factor in Normal and Regenerating Cavernous Nerves

SHH regulates BDNF in the normal and regenerating PG/CN. BDNF is part of the mechanism of how SHH promotes regeneration, thus providing an opportunity to further manipulate the nerve microenvironment with combination therapy to enhance regeneration. Bond CW, Angeloni N, Harrington D, Stupp S, and Podlasek CA. Sonic hedgehog regulates brain‐derived neurotrophic factor in normal and regenerating cavernous nerves. J Sex Med 2013;10:730-737.