PARP Inhibition Restores Erectile Function by Suppressing Corporal Smooth Muscle Apoptosis in Diabetic Rats

Over‐activation of penile PARP pathway in diabetic rats enhances corporal apoptosis via energy depletion, suppression of Akt phosphorylation, and activation of the mitochondrial apoptotic pathway, which results in ED; these event could be prevented by treatment with 3‐AB. Li WJ, Zhou J, Li B, Wang H, Peng YB, and Wang Z. PARP inhibition restores erectile function by suppressing corporal smooth muscle apoptosis in diabetic rats.