Role of 5-HT Receptor Antagonists in Mediating Intracavernous Pressure Response Induced by Fluvoxamine in Conscious Rats

These findings demonstrated that ICP is regulated at the supraspinal level when endogenous serotonin is increased by fluvoxamine. Furthermore, ICP is facilitated by 5-HT2C-receptors and inhibited by 5-HT1A-receptors in the rat brain. Aizawa N, Ishizuka O, Ogawa T, Mizusawa H, Igawa Y, and Nishizawa O. Role of 5-HT receptor antagonists in mediating intracavernous pressure response induced by fluvoxamine in conscious rats.