Intracavernous Growth Differentiation Factor‐5 Therapy Enhances the Recovery of Erectile Function in a Rat Model of Cavernous Nerve Injury

Intracavernous injection of low (0.4 µg) or intermediate‐concentration GDF‐5 (2 µg) was effective in preserving erectile function in a rat model of neurogenic erectile dysfunction. The underlying mechanism appears to involve neuron preservation and antiapoptosis. Fandel TM, Bella AJ, Lin G, Tantiwongse K, Lin C‐S, Pohl J, and Lue TF. Intracavernous growth differentiation factor‐5 therapy enhances the recovery of erectile function in a rat model of cavernous nerve injury. J Sex Med 2008;5:1866-1875.