کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4279808 | 1611545 | 2011 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Adverse effects of preoperative steroid use on surgical outcomes Adverse effects of preoperative steroid use on surgical outcomes](/preview/png/4279808.png)
BackgroundPreoperative steroid use has been associated with increased postoperative complications. We sought to establish these risks using data from the National Surgical Quality Improvement Program (NSQIP).MethodsNSQIP public use files from 2005 to 2008 were analyzed for preoperative steroid use and postoperative adverse events.ResultsOf 635,265 patients identified, 20,434 (3.2%) used steroids preoperatively. Superficial surgical site infections (SSI) increased from 2.9% to 5% using steroids (odds ratio, 1.724). Deep SSIs increased from .8% to 1.8% (odds ratio, 2.353). Organ/space SSIs and dehiscence increased 2 to 3-fold with steroid use (odds ratios, 2.469 and 3.338, respectively). Mortality increased almost 4-fold (1.6% to 6.0%; odds ratio, 3.920). All results were significant (P < .001).ConclusionsPrevious concerns related to surgical risks in patients on chronic steroid regimens appear valid. These results may assist in counceling patients regarding the increased risk of surgery. They may also help the surgeon plan and modify the procedure if possible.
Journal: The American Journal of Surgery - Volume 201, Issue 3, March 2011, Pages 305–309