کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4279926 1611548 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evaluation of empiric antibiotic use in surgical sepsis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
Evaluation of empiric antibiotic use in surgical sepsis
چکیده انگلیسی

BackgroundWe performed an evaluation of antimicrobial guidelines for patients with surgical sepsis.MethodsThe purpose of this study was to validate current empiric antibiotic recommendations in our sepsis protocol based on the suspected site of infection. The primary objective was to assess the appropriateness of empiric antibiotic recommendations and to determine if initial empiric antibiotics provided adequate coverage compared with sensitivity data (accuracy). Secondary end points included antibiotic protocol compliance, intensive care unit (ICU)-free days, and mortality.ResultsAppropriate antibiotics were prescribed in 82% of patients. Of the culture-positive patients, 72% received accurate antibiotics. ICU-free days were greater for patients in the compliant group (14.5 vs 8.4; P = .014). Hospital mortality was greater in patients who were noncompliant with protocol recommendations (22% vs 17%; P = .44).ConclusionsOur current antibiotic guidelines provide appropriate and accurate antimicrobial coverage. Noncompliance with the antibiotic protocol resulted in fewer ICU-free days and increased hospital mortality in surgical sepsis patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Surgery - Volume 200, Issue 6, December 2010, Pages 776–782
نویسندگان
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