کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4280999 | 1611571 | 2009 | 6 صفحه PDF | دانلود رایگان |
BackgroundWe hypothesized that colectomy for fulminant Clostridium difficile colitis (CDC) before organ failure would be associated with decreased mortality.MethodsData were retrospectively collected on patients operated on for CDC between 2000 and 2007. Variables examined included age, sex, immunodeficiency, recurrent CDC, vasopressor requirement, acute respiratory failure, acute renal failure, white blood cell count, and stress ulcer prophylaxis. Univariate and multivariate analyses were performed to identify predictors of mortality.ResultsDuring this period, 6,841 patients were diagnosed with CDC and 69 patients underwent surgery. Independent predictors of mortality were age >65 years (odds ratio [OR] 6.8, confidence interval [CI] 1.4–32.3, P = .016), acute respiratory failure (OR 5.4, CI 1.6–18.1, P = .007), and acute renal failure (OR 3.8, CI 1.1–13.1, P = .035).ConclusionsColectomy before the development of organ failure is associated with decreased mortality in patients with fulminant CDC, especially in those >65 years old.
Journal: The American Journal of Surgery - Volume 197, Issue 3, March 2009, Pages 302–307