کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4281180 1611589 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Outcome determinants in acute pancreatitis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
Outcome determinants in acute pancreatitis
چکیده انگلیسی

Acute pancreatitis is a protean disease, which usually takes an uneventful course to complete recovery. However, in about 25% of patients severe disease develops and may ultimately evolve to a life-threatening condition. New insights into the pathomechanism and natural course led to the identification of risk factors associated with enhanced morbidity and mortality. Prognosis or outcome is usually reflected by nonsurvival; however, not all known complications or risk factors are necessarily life-threatening and ultimately do not interfere with outcome. Among the local complications, such as necrosis and infection, only infected necrosis represents a definite outcome determinant. Since the turn of the millennium, pancreatitis-related organ failure, occurring either early or persistently, has gained considerable headway as a predominant risk factor of mortality and even seems to outweigh local complications in this respect. Other recent clinical factors include abdominal compartment syndrome, obesity, and comorbidity as relevant outcome determinants. The current review provides an overview about established risk factors determining the outcome of acute pancreatitis based on the latest and most important literature.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Surgery - Volume 194, Issue 4, Supplement, October 2007, Pages S39–S44
نویسندگان
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