کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4281354 1611595 2007 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A review of the prognostic factors in patients with recurrence after liver resection for hepatocellular carcinoma
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
A review of the prognostic factors in patients with recurrence after liver resection for hepatocellular carcinoma
چکیده انگلیسی

BackgroundLiver transplantation achieves better results when hepatocellular carcinoma fits the Milan criteria. This study investigated predictors of recurrent hepatocellular carcinoma exceeding the Milan criteria.MethodsAmong 285 patients with hepatocellular carcinoma fitting the Milan criteria who underwent curative resection, 143 patients suffered initial recurrence (92 had tumors fitting the criteria) and 71 patients suffered a second recurrence (40 conforming tumors).ResultsSurvival after hepatectomy was significantly worse when initial recurrence was nonconforming. Similarly, survival after initial recurrence was significantly worse when the second recurrence was nonconforming. A preoperative increase of protein induced by vitamin K absence/antagonist II, a tumor diameter of 3 cm or greater, age of 65 years or younger, and intraoperative blood transfusion increased the risk of nonconforming initial recurrence.ConclusionsLiver transplantation should be considered initially for younger patients with hepatocellular carcinoma fitting the Milan criteria, larger tumors, and an increase of protein induced by vitamin K absence/antagonist II.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Surgery - Volume 193, Issue 4, April 2007, Pages 431–437
نویسندگان
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