Actinomyces-induced inflammatory myofibroblastic tumor of the colon: A rare cause of an abdominal mass: Akbulut et al. inflammatory myofibroblastictumor due to actinomyces spp

• Abdominal inflammatory myofibroblastic tumor (IMFT) macroscopically appear as mass lesions that grow slowly and sometimes cause destruction of adjacent structures. The exact diagnosis can only be made with histopathological examination of permanent tissue. Resection with negative surgical borders is the most suitable surgical technique. The same principles also apply to IMFT developing on the basis of actinomycosis because it is quite difficult to predict at the preoperative period that the lesion developed secondary to actinomycosis. The diagnosis is almost always made with histopathological examinations. Affected patients should receive prolonged antibiotherapy once the diagnosis is confirmed.

IntroductionInflammatory myofibroblastic tumors (IMFTs) are neoplastic lesions that are either benign or have low-grade malignancy potential. Although the etiopathogenesis is not entirely clear, many factors play a role in their development, including trauma, autoimmune disorders, and infectious and inflammatory processes. However, IMFTs caused by Actinomyces spp. infection are rare, with a limited number of cases reported in the literature.Presentation of caseA 30-year-old woman was admitted to our clinic with abdominal pain and a palpable abdominal mass. Contrast-enhanced computed tomography revealed a tumoral lesion (11 × 10 × 7 cm) in the right colon. A right hemicolectomy and ileocolic anastomosis were performed, during which almost complete obstruction of the lumen by the 7.5 × 7.0 × 5.0 cm tumor was observed. Histopathology and immunohistochemical findings revealed that the tumor was consistent with an IMFT that developed from an Actinomyces infection. The patient was then placed on amoxicillin and doxycycline therapy.ConclusionThis case demonstrates that the development of IMFT secondary to actinomycosis is difficult to predict in the preoperative period. Once an exact diagnosis is confirmed by histopathologic examination, affected patients should receive prolonged antibiotherapy.