کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4297231 | 1288251 | 2006 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Clinical and Pathological Features of Allen's Type C Classification of Resected Combined Hepatocellular and Cholangiocarcinoma: A Comparative Study with Hepatocellular Carcinoma and Cholangiocellular Carcinoma
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
عمل جراحی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Clinical and Pathological Features of Allen's Type C Classification of Resected Combined Hepatocellular and Cholangiocarcinoma: A Comparative Study with Hepatocellular Carcinoma and Cholangiocellular Carcinoma Clinical and Pathological Features of Allen's Type C Classification of Resected Combined Hepatocellular and Cholangiocarcinoma: A Comparative Study with Hepatocellular Carcinoma and Cholangiocellular Carcinoma](/preview/png/4297231.png)
چکیده انگلیسی
The clinical features of Allen's type C of combined hepatocellular and cholangiocarcinoma (cHCC-CC) are not well known. In this study, we aim to define the clinicopathologic features of cHCC-CC and to evaluate the preoperative diagnosis and surgical treatment results in comparison with those of hepatocellular carcinoma (HCC) and cholangiocellular carcinoma (CCC). We retrospectively analyzed 13 patients with cHCC-CC, 509 patients with HCC, and 41 patients with CCC treated in our hospital within past two decades. Viral hepatitis B or C backgrounds were more prominent in HCC and cHCC-CC groups than in the CCC group. Elevated serum alpha-fetoprotein (AFP) levels were found in 60.3% of HCC patients and in 46.2% of cHCC-CC patients. Only one patient of cHCC-CC was correctly diagnosed before surgery. The postoperative survival rates between the cHCC-CC and HCC or the CCC group were not significantly different. Both intrahepatic and extrahepatic postoperative recurrences were frequent in cHCC-CC patients, and CCC component recurrences were more frequently seen. In conclusion, the preoperative diagnosis is difficult; liver masses similar to those of HCC, together with moderately elevated serum AFP and CA19-9 levels, are reliable indicators of cHCC-CC. Surgical resection of this tumor yields results intermediate between those of HCC and CCC in character. More cases are needed to further define the characteristics of this tumor.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Gastrointestinal Surgery - Volume 10, Issue 7, JulyâAugust 2006, Pages 987-998
Journal: Journal of Gastrointestinal Surgery - Volume 10, Issue 7, JulyâAugust 2006, Pages 987-998
نویسندگان
Di M.D., Hiroaki M.D., Ph.D., Masato M.D., Hiroshi M.D., Shigeru M.D., Ph.D., Atsushi M.D., Ph.D., Yutaka M.D., Ph.D., Koji M.D., Ph.D., Keizo M.D., Ph.D., Morito M.D., Ph.D.,