Changes of insulin-like growth factor-II and insulin-like growth factor binding protein-3 in cerebrospinal fluid of children with tuberculous meningitis

IGFs and IGFBPs are involved in the pathophysiological process of tuberculous meningitis, as well as the glucose and protein metabolism in cerebrospinal fluid. ? The IGF-? and IGFBP-3 contents in cerebrospinal fluid can be used as the auxiliary indicators to differentially diagnose tuberculous meningitis and viral encephalitis.